상황버섯, Phellinus linteus 계통과 Phellinus baumii 의 항 혈소판 응집 효과
Inhibitory effects of Sanghwang mushrooms, Phellinus linteus strains and Phellinus baumii, on platelet aggregation
The fruiting bodies of Sanghwang mushrooms, Phellinus linteus HN1009K (PLH) and Phellinus linteus (Korea Sanghwang, PLK), and Phellinus baumii (Jangsu Sangwhang, PB), were extracted with 70% methanol. The methanolic extracts of different concentrations (5–200 μg/ml) showed inhibitory effects of 20–95% on plated aggregation induced by collagen (2.5 ug/ml), ADP (10 uM), and thrombin (0.1 U/ml). The PLH, PLK, and PB extracts (200 ug/ml) reduced ATP release from ADP-activated platelets by 50¬60%. These results suggest that the methanolic extracts from Sanghwang mushrooms inhibit platelet aggregation.
목차
ABSTRACT 서론 재료 및 방법 실험재료 혈소판의 준비 혈소판응집억제효과 검정 ATP release 분석 결과 및 고찰 상황버섯 메탄올 추출물의 혈소판 응집억제 효과 상황버섯 메탄올 추출물의 ATP release 감소효과 적요 감사의 글 References
저자
강희완 [ Hee-Wan Kang | 한경대학교원예생명과학과, 경대학교유전공학연구소 ]
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