Earticle

초록

영어

This study was initiated to investigate antioxidant, anti-acetylcholinesterase, and xanthine oxidase inhibitory activities and properties of fruiting bodies, mycelia, and fermentation culture filtrates from Phellinus igniarius. The contents of total phenols and flavonoid of fruit bodies, mycelia, and culture filtrate were 15.35-1.36 mg/g, 10.35-7.85 mg/g, and 8.25-5.36 mg/g. The 1,1- diphenyl-1-picrylhydrazyl (DPPH) radical scavenging abilities of the extracts from the fruiting bodies, mycelia, and culture filtrates were 90.25-95.60%, 78.82-85.24%, and 76.32-82.50% at 50-400 μg/mL, respectively. The chelating ability of fruiting body extract on ferrous ions was higher than those of mycelia and culture filtrates tested. The anti-acetylcholinesterase inhibitory activity of the fruiting body extract at 400 μg/mg exhibited 91.10% on AChE, which is lower than that of positive control, galanthamine (94.82%). The xanthine oxidase inhibitory activities of the fruiting bodies, mycelia, and culture extract were 85.47%, 78.13%, and 72.49% at 400 μg/mL, respectively. Overall, the fruiting body extract has better anti-acetylcholinesterase, antioxidant and xanthine oxidase inhibitory activities than those from mycelia and culture filtrate.

목차

ABSTRACT
 Introduction
 Materials and Methods
  Specimens and fungal isolate
 Preparation of the Extracts
  Fruiting body extract
  Mycelia extract
  Culture filtrate
  Assay for total phenolics
  Assay for total flavonoid
  Scavenging effect on DPPH radicals
  Chelating effect on ferrous ions
  Xanthine oxidase inhibitory activity
  Acetylcholinesterase inhibitory activity
 Results and Discussions
  Total phenolics and flavonoid
  DPPH scavenging effect on free radicals
  Chelating effects on ferrous ions
  Xanthine oxidase inhibitory activity
  Acetylcholinesterase inhibitory activity
 Acknowledgemen
 References

저자

• Ga-Heon Jin [ Department of Ophthalmic Optics, Shinheung University ]
• Min Woong Lee [ Department of Life Sciences, Dongguk University ]
• Kyung Hoan Im [ Division of Life Sciences, Incheon National University ]
• Tae Soo Lee [ Division of Life Sciences, Incheon National University ] Corresponding author

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