Earticle

초록

영어

Evolutionary processes such as recombination and natural selection usually develop over extended periods of time; however, they get accelerated in cases of hybridization. Interspecies hybrids exhibit novel genome which are exposed to natural selection, thus provides a key to unravel the ultimate causes of adaptation and speciation. On the other hand, with rapid upsurge in demand for stronger food security has been confronting us on daily basis. Lately, the scientists have started to gather are now attracted by specific extraordinary traits of different animals by way interspecies hybridization combining the superior genetic material from different animals. Besides, this technology could also explore new life saving vaccines and medicines and also would find beneficial in conserving wild heritage of endangered and critical species. Several researchers have also done commendable work on interspecies hybridization with some degree of success. Nevertheless, lots of obstacles and hurdles still pose for this phenomenal technology to reach to its final destination. This review will point out the hurdles on interspecies hybridization in reference to the natural mating and somatic cell nuclear transfer (SCNT).

목차

ABSTRACT
 INTRODUCTION
 Interspecies hybridization and hybrid
 Advantages of Interspecies hybridization
 Disadvantages of interspecies hybridization
 Hurdles in interspecies hybridization
  Isolation Mechanism
  Inability to invade oocyte wall by sperm
  Adverse effect of the Oviductal factors
  Polarity in Hybridization
  Large fetus size
  Unavailability of suitable foster mother
  Failure to Nuclear Reprogramming
  Mitochondrial/genomic DNA incompatibility
  Zygotic Genome Activation (ZGA) Failure
  Improper placenta formation and maternal immune response
 Interspecies Hybridization and Future AnimalProduction
 Conclusion
 LITERATURE CITED

저자

• 아부 무사 레자 [ Abu Musa Md. Talimur Reza | 강원대학교 동물생명과학대학 ]
• 이성진 [ Sung-Jin Lee | 강원대학교 동물생명과학대학 ]
• 나레시쿠마 싱 [ Naresh Kumar Singh | 강원대학교 동물생명과학대학 ] Corresponding author

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