운동형태에 따른 성인 rats subventricular zone의 BrdU-labeled cells number 및 striatum의 NGF 수준 변화
Changes of BrdU-labeled cells number of Subventricular zone and NGF protein level of Striatum in Adults rats following Exercise types
We investigated the effects of exercise types on the BrdU-labeled cells number of the subventricular zone(SVZ) and the level of nerve growth factor(NGF) protein of striatum in the adult rats over a period of 8 weeks. We divided 24 male SD rats into 3 groups: (1) a control group(CON, n=8), (2) a swimming exercise group(SWE, n=8), (3) a treadmill exercise group(TRE, n=8). The SWE and TRE were made to perform their respective exercise type for 5 days per week over a period of 8 weeks. The BrdU-labeled cells number and NGF level increased significantly in the SWE and TRE, compard to the CON(p<.001, p<.01). Specially, a significant increase of BrdU-labeled cell number of SVZ were observed in the SWE. These results show that regular exercise across a period of 8 weeks increased the BrdU-labeled cells number of SVZ and also increased the level of NGF of striatum in the adult rats.
목차
Ⅰ. 서론 Ⅱ. 연구방법 1. 실험대상 2. 실험절차 3. 조직채취 4. SVZ의 BrdU-labeled cells number by BrdU immunohistochemistry 5. NGF 수준의 변화 6. 자료처리 Ⅲ. 결과 1. BrdU-labeled cells number의 변화 2. NGF 수준의 변화 Ⅳ. 논의 Ⅴ. 결론 참고문헌 ABSTRACT